Figure 1

Characteristics of HCPT-loaded nanoparticles. (A-C): UV spectrum of HCPT detected by ultraviolet spectrophotometry. At wavelengths of 326 and 368 nm, both the HCPT standard sample (A) and the mixture of HCPT and PBLG/PEG (B) had high absorbency, but the absorbency of HCPT-loaded PBLG/PEG nanoparticles (C) was greatly decreased. (D) The morphology of HCPT-loaded nanoparticles was found under scanning electron microscopy (× 160 000) to be a core-shell structure, spherical or elliptical, with a smooth surface. The hydrophobic central core was a grayish area, approximately 200 nm in diameter. The hydrophilic shell was a bright white ring, approximately 30 nm thick.