Figure 4
Effects of CD70 and CD80 co-expression by single transduced tumor cells on tumor growth in an established model. 4A: 105 B16.F10 wt (control cells), or CD70 and CD80 double transduced B16.F10, or CD70 and CD80 single transduced B16.F10 were injected s.c. on day 0 into female C57BL/6 mice. 4B: 105 TS/A wt (control cells), or CD70 and CD80 double-transfected TS/A, or CD70 and CD80 single-transfected TS/A were injected s.c. on day 0 in female BALB/c mice. Tumor growth was monitored twice a week. The results are expressed as mean size (mm2) of tumors from groups that each contain five mice ± SD. The data represent mean +/- SD of a single experiment representative of three.pouet