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Table 1 Toxicity of the isopropanolic extracts against lung (A-549), colon carcinoma (HT-29), and brine shrimp assays

From: A comparison between two brine shrimp assays to detect in vitrocytotoxicity in marine natural products

  A-549 HT-29 HI-12 h HI-24 h HI-48 h M-12 h M-24 h M-48 h
Sponges         
Chondrosia tenochca 16 22 19 15 11 0 0 77
Hyatella sp. 161 129 28 51 46 13 15 40
Mycale parishii 4 25 44 62 64 5 10 10
Dysidea sp. 106 88 35 50 50 0 3 59
Gorgonians         
Lophogorgia sp. 33 26 51 72 81 0 0 0
Pacifigorgia adamsii 127 86 56 72 76 8 68 68
Muricea sp. 93 131 42 64 89 40 83 83
Tunicates         
Polyclinum laxum 87 102 3.4    67 96.5 95.5
Echinoderms         
Toxopneustes roseus 14 14 8.4 24.4 29.6 17 96.5 95.5
Isostichopus fuscus 31 13 8.4 24.4 29.8 32 91.5 95.5
Holoturia impatiens 181 84     4.3 23.7 60
Pseudocus californica 122 139 17.9 27.8 30 1.5 18 58
Phataria unifascialis 29 10 5.6 8.8 0.2 1.8 8.7 20
Pharia pyramidata 194 88 17.9 27.8 30 1.5 0.5 93
Macroalgae         
Colpomenia tuberculata 91 91 4.4 12.8 19.1 0 8.3 8.3
Enteromorpha intestinalis 2 47 8 20.3 20.6 1.8 5 38.1
Gelidiopsis tenuis 81 91 5.6 8.5 18.6 0 3.33 0.8
Ralfsia hesperia 11 7 8 5.1 0.9 1.8 2.5 13.1
Ceramium sp. 4 5 7.4 18 24.1 0 0.8 0.8
Codium dichotomum 110 -9 2.6 0.5 2.8 0 0 0
  1. The percentage of growth inhibition at 50 μg/ml is shown below A-549 and HT-29. The percentage of hatch inhibition, and percentage of mortality at 1000 μg/ml at 12, 24 and 48 h of exposure are shown below HI (brine shrimp hatchability test)and M (brine shrimp lethality test).