Skip to main content

Table 1 Toxicity of the isopropanolic extracts against lung (A-549), colon carcinoma (HT-29), and brine shrimp assays

From: A comparison between two brine shrimp assays to detect in vitrocytotoxicity in marine natural products

 

A-549

HT-29

HI-12 h

HI-24 h

HI-48 h

M-12 h

M-24 h

M-48 h

Sponges

        

Chondrosia tenochca

16

22

19

15

11

0

0

77

Hyatella sp.

161

129

28

51

46

13

15

40

Mycale parishii

4

25

44

62

64

5

10

10

Dysidea sp.

106

88

35

50

50

0

3

59

Gorgonians

        

Lophogorgia sp.

33

26

51

72

81

0

0

0

Pacifigorgia adamsii

127

86

56

72

76

8

68

68

Muricea sp.

93

131

42

64

89

40

83

83

Tunicates

        

Polyclinum laxum

87

102

3.4

  

67

96.5

95.5

Echinoderms

        

Toxopneustes roseus

14

14

8.4

24.4

29.6

17

96.5

95.5

Isostichopus fuscus

31

13

8.4

24.4

29.8

32

91.5

95.5

Holoturia impatiens

181

84

   

4.3

23.7

60

Pseudocus californica

122

139

17.9

27.8

30

1.5

18

58

Phataria unifascialis

29

10

5.6

8.8

0.2

1.8

8.7

20

Pharia pyramidata

194

88

17.9

27.8

30

1.5

0.5

93

Macroalgae

        

Colpomenia tuberculata

91

91

4.4

12.8

19.1

0

8.3

8.3

Enteromorpha intestinalis

2

47

8

20.3

20.6

1.8

5

38.1

Gelidiopsis tenuis

81

91

5.6

8.5

18.6

0

3.33

0.8

Ralfsia hesperia

11

7

8

5.1

0.9

1.8

2.5

13.1

Ceramium sp.

4

5

7.4

18

24.1

0

0.8

0.8

Codium dichotomum

110

-9

2.6

0.5

2.8

0

0

0

  1. The percentage of growth inhibition at 50 μg/ml is shown below A-549 and HT-29. The percentage of hatch inhibition, and percentage of mortality at 1000 μg/ml at 12, 24 and 48 h of exposure are shown below HI (brine shrimp hatchability test)and M (brine shrimp lethality test).