Figure 5From: Reduction in C-terminal amidated species of recombinant monoclonal antibodies by genetic modification of CHO cellsPAM gene copy numbers for 154 ZFN clones from CHO Der2 parental cell line transfected using ZFN mRNA. The two clones (K62 and K68) identified as knocked-out for all PAM gene copies at the genomic DNA level. The copy number was determined by qPCR, and the data are means ± standard deviations of two technical replicates.Back to article page