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Table 9 Target genes for homologous recombination

From: Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set

Target gene Vector Modification
CFTR[7]§ CH242-248P18 (>100 kb) ATG-STOP
DMD[42]§ CH242-9G11 (>100 kb) Δ exon 52
GGTA1 CH242-21 F3 (>100 kb) ATG-STOP
APC[64]§ 12.5 kb STOP
KRAS 13.5 kb Point mutation
JAK3 13.8 kb Δ exon 2-5
  1. § See indicated references.