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Table 9 Target genes for homologous recombination

From: Factors influencing the efficiency of generating genetically engineered pigs by nuclear transfer: multi-factorial analysis of a large data set

Target gene

Vector

Modification

CFTR[7]§

CH242-248P18 (>100 kb)

ATG-STOP

DMD[42]§

CH242-9G11 (>100 kb)

Δ exon 52

GGTA1

CH242-21 F3 (>100 kb)

ATG-STOP

APC[64]§

12.5 kb

STOP

KRAS

13.5 kb

Point mutation

JAK3

13.8 kb

Δ exon 2-5

  1. § See indicated references.
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BMC Biotechnology

ISSN: 1472-6750

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