Visualisation and Quantification of Apoptosis in Constructs by Caspase-3 IHC. There was a significant reduction in the number of apoptotic cells seen in constructs containing GBP-1 EPC compared to EV-EPC. * P< 0.05 vs. EV EPC. N= 4 animals per group. 2 independent cross section analyses per animal and construct were performed, i.e. 8 values per group were obtained and evaluated including statistical analysis. Scale Bar = 50 μm.