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Table 3 Values of independent variables at different levels of CCD design

From: Enhanced cell disruption strategy in the release of recombinant hepatitis B surface antigen from Pichia pastoris using response surface methodology

Independent variable

Levels

 

-α (1.682)

−1

0

+1

+α (1.682)

Number of passes (times)

12

15

20

25

28

Biomass concentration (g/L)

4.41

5.74

7.70

9.65

10.98

Pulse pressure (bar)

327.28

600

1,000

1,400

1672.72

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BMC Biotechnology

ISSN: 1472-6750

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