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Table 2 Media components and their ranges from literature studies used for optimization

From: Enhanced itaconic acid production in Aspergillus niger using genetic modification and medium optimization

Media optimization Value reference
Source   min (g/L) max (g/L)  
C Glucose 50 140 [9, 10, 13]
N NaNO3 0.5 2.4 [4]
  NH4SO4 2.36 2.36 [27]
  NH4NO3 3.1 5 [9, 10]
P KH2PO4 0.11 3 [4, 27]
Mg MgSO4 x 7 H2O 0.24 2.2 [4, 9]
Cu CuSO4 x 5 H2O 0 0.0025 [4]
Fe Fe2SO4 x 7 H2O 0.0006 0.0138 [4, 28]
  FeCl3 0.0006 0.0001 [4, 9]
Mn MnCl2 x 4 H2O 0 0.007 [11, 27]
Zn ZnSO4 x 7 H2O 0.0006 0.022 [12]
Ni NiCl2 x 6 H2O 0 0.0005 [4]
K KCl 0.52 0.52 [4]
  NaCl 0,074 2 [4, 27]
  CaCl2 * 2H2O 0,13 0,2 [4, 27]