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Table 2 Susceptibilities of S. rimosus mutants to several drugs

From: Molecular cloning and functional characterization of an ATP-binding cassette transporter OtrC from Streptomyces rimosus

Antibiotics (μg/ml)

M4018/pSET152

M4018/pSEC

M4018/pKCΔotrC

Ampicillin

500

1500

100

Rifampicin

200

200

200

Oxytetracycline

1500

2500

1000

Doxorubicin

500

1000

100

Ethidium bromide

4

8

4

Vancomycin

1

500

-

Ofloxacin

20

400

4

Erythromycin

2

2

2

Streptomycin

+

+

+

  1. ‘+’, cell growth could not be inhibited by the antibiotic; ‘-’, cell growth was completely inhibited.