Figure 2

Recombinant human Pf MSP1 ₁₉ -specific IgA is functional. Stimulation of neutrophil NADPH oxidative bursts using 50 μg of IgA attached to GST-PfMSP1₁₉-coated microtiter plates (open squares), or 50 μg of IgA attached directly to the bottom of the plate (open triangles) or no Ab (open curcles). Data are presented as mean chemiluminescence (CL; arbitary units) from triplicate wells using neutrophils from a single human donor as previously described [3, 12, 13].