Measurement principle of the BioLector (A) and experimental setup for the Robo-Lector (B). The BioLector provides a system for cultivating microorganisms in a microtiter plate (MTP) inside an incubation chamber. The MTP is continuously shaken to provide sufficient oxygen to the culture. An optical measurement system continuously monitors biomass concentration and fluorescent products. The Robo-Lector setup consists of a BioLector integrated into a pipetting robot, enabling fully automated high throughput cultivation experiments in a MTP format.