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Table 3 G-scores of the 10 selected scFvs.

From: Isolation of a nanomolar scFv inhibiting the endopeptidase activity of botulinum toxin A, by single-round panning of an immune phage-displayed library of macaque origin

scFv

chain

G-score

2A3

VH

-0.826

 

VL

-0.937

1G7

VH

-0.562

 

VL

-2.689

2A6

VH

-1.201

 

VL

-0.879

2F2

VH

0.518

 

VL

-1.011

2G10

VH

-0.709

 

VL

-0.812

2H8

VH

-0.530

 

VL

-0.901

3C6

VH

-2.124

 

VL

0.070

3C11

VH

-0.310

 

VL

-0.541

3G12

VH

-1.199

 

VL

-0.898

2D1

VH

-1.341

 

VL

-0.845

  1. The human-like character of the 10 selected scFvs was evaluated through the calculation of G-scores, to indirectly predict their immunogenicity.