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Table 2 Neutralizing activity and affinity of anti-VLY scFvs and the respective MAbs

From: Generation of recombinant single-chain antibodies neutralizing the cytolytic activity of vaginolysin, the main virulence factor of Gardnerella vaginalis

Anti VLY scFv and MAb IC50, M Kd, M
scFv 9B4 (VL-VH) 3.7 × 10-8 1.1 × 10-8
scFv 9B4 (VH-VL) 5.1 × 10-8 1.5 × 10-8
scFv 23A2 (VL-VH) 1.1 × 10-7 9.2 × 10-8
scFv 23A2 (VH-VL) 1.5 × 10-7 9.8 × 10-8
MAb 9B4 6.7 × 10-11 2.9 × 10-10
MAb 23A2 4.8 × 10-10 1.2 × 10-10