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Table 3 Statistical analysis of 2-factorial experimental design at various significant process parameters for L-dopa production by A. niger GCBT-8

From: Production of 3,4-dihydroxy L-phenylalanine by a newly isolated Aspergillus niger and parameter significance analysis by Plackett-Burman design

Significant process parameters

Sum mean values

F-value

Degree of freedom

Probability <p>

A

1.364

0.242

1

0.087

B

1.925

0.565

1

0.076

C1

1.981

0.804

1

0.069

C2

2.186

1.082

2

0.062

D

2.862

1.243

2

0.048

E

3.695

1.426

3

0.026

Correlation

0.012E+0025

   
  1. CM - 19.24; R2 - 0.238. The letters represent significant process parameters (time course, initial pH, glucose levels by intact and grinded mycelia, inorganic and organic nitrogen sources, potassium sources) for L-dopa production.