Skip to main content
Figure 5 | BMC Biotechnology

Figure 5

From: Intranasal vaccination with messenger RNA as a new approach in gene therapy: Use against tuberculosis

Figure 5

Immunostimulatory activity of mRNA-Hsp65. Five BALB/c mice per group mice were immunized with one dose of mRNA-Hsp65 (10 μg per mouse in 100 μL volume). Not immunized group received only the Ringer's solution. Two weeks after the immunization splenic cells are isolated and stimulated with 20 μg/ml of Hsp65 protein, 48 hours after stimulation the production of (A) IFN-gamma and (B) TNF-alpha by were determined by ELISA. *p < 0.05 were considered significant when compared to not immunized group.

Back to article page

BMC Biotechnology

ISSN: 1472-6750

Contact us