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Figure 4 | BMC Biotechnology

Figure 4

From: Exploitation of the interaction of measles virus fusogenic envelope proteins with the surface receptor CD46 on human cells for microcell-mediated chromosome transfer

Figure 4

Detection of chromosome transfer from the microcell to the donor cell. Recipient cells exposed to the microcells, and selected by Blasticidin treatment, were analyzed by fluorescence in situ hybridization to detect cells containing the transferred HAC. The HAC is delineated using an alphoid satellite probe derived from human chromosome 21, and is shown in red (arrow). The alphoid satellite probe detects endogenous chromosomes 13 and 21 (arrowhead), in addition to the HAC, due to their sequence similarity.

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BMC Biotechnology

ISSN: 1472-6750

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