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Table 6 In vitro inhibition of Notch cleavage by AD28 and AD115.

From: Phenotypic analysis of images of zebrafish treated with Alzheimer's γ-secretase inhibitors

Cpd

Conc.

In vitro Inhibition of Notch Cleavage

DMSO

0.10%

-

DAPT

100 μM

+

Gleevec

100 μM

-

AD28

100 μM

+

AD94

100 μM

-

AD95

100 μM

-

AD115

100 μM

+