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Table 2 Breakdown of validated variant calls across Cincinnati and Harvard arrays

From: High-throughput detection of mutations responsible for childhood hearing loss using resequencing microarrays

  Harvard (26 arrays) Cincinnati (13 arrays)
  Total Per array average Total Per array average
Total variants 411 16 192 15
Total unique variants 50 16 61 15
Common variants detected     
   Correctly called 292 11 141 11
   No call 57 2.2 23 1.8
   Missed call (het vs. hom) 8 0.3 10 0.8
   Called wild-type 10A 0.4 0 0
Rare variants detected (1 case)     
   Correctly called 30 1.2 10 0.8
   No call 12 0.5 5 0.4
   Missed call (het vs. hom) 2 0.1 0 0
   Called wild-type 0 0 3B 0.2
  1. A: All 10 wild-type calls (false negatives) were due to a single repeatedly miscalled common benign variant in MYO7A (4755T>C; S1585S).
  2. B: False negatives were from CDH23 (2761C>T, L921L), MYO7A (4831C>T, L1611L) and KCNQ1 (1185C>T, F395F)