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Table 5 Results of panning experiments on RNA targets using secondary libraries

From: A surrogate-based approach for post-genomic partner identification

Target Primary Secondary Target Specific Target Specific
  Binder Binder (%) Binders: Primary Binders: Secondary
  (%)   (%) (%)
APP 78 95 9 40
HCV 86 98 13 17
IGF-1 77 99 4 18
  1. Clones were categorized as specific binders if they had a binding ratio of target:irrelevant ≥ 2.0, as described in Table 2 above. Comparison of percentage specific binders from pannings of primary libraries (expressing random peptides) vs. secondary libraries (based on target-specific primary surrogates) is shown in this Table.