Classification | Target | Ba-Asp |
---|---|---|
Organ toxicity | Hepatotoxicity | Active |
Toxicity end points | Carcinogenicity | Inactive |
Immunotoxicity | Active | |
Mutagenicity | Inactive | |
Cytotoxicity | Inactive | |
Tox21-Nuclear receptor signaling pathways | Aryl hydrocarbon Receptor (AhR) | Inactive |
Androgen Receptor (AR) | Inactive | |
Androgen Receptor Ligand Binding Domain (AR-LBD) | Inactive | |
Aromatase | Active | |
Estrogen Receptor Alpha (ER) | Active | |
Estrogen Receptor Ligand Binding Domain (ER-LBD) | Active | |
Peroxisome Proliferator Activated Receptor Gamma (PPAR-Gamma) | Inactive | |
Tox21-Stress response pathways | Nuclear factor (erythroid-derived 2)-like 2/antioxidant responsive element (nrf2/ARE) | Inactive |
Heat shock factor response element (HSE) | Inactive | |
Mitochondrial Membrane Potential (MMP) | Inactive | |
Phosphoprotein (Tumor Supressor) p53 | Inactive | |
ATPase family AAA domain-containing protein 5 (ATAD5) | Inactive |