Mutations |
μ (h−1) | Yr5p (−) |
---|
PDH | 0.37 | 4.83 |
PDH, LDH | 0.22 | 6.15 |
PDH, ICL | 0.22 | 6.15 |
PDH, MALS | 0.22 | 6.15 |
PDH, GLUN | 0.42 | 3.54 |
- Simulations were performed to maximized biomass while fixing to zero the flux through the following enzymes: ICL Isocitrate lyase, LDH Lactate dehydrogenase, MALS Malate synthase, GLUN Glutaminase