Fig. 3From: Potent long-acting rhFGF21 analog for treatment of diabetic nephropathy in db/db and DIO miceEffect of PEG-FGF21 and FGF21 on renal lipid levels in DIO mice. Cholesterol content in renal cortical tissue (a); Triglyceride content in renal cortical tissue (b); Lipid hydroperoxides (LPO) content in renal cortical tissue (c); 24-h urinary levels of 8-isoprostane; urinary excretion of 8-isoprostane was corrected by urinary creatinine (d). Values are means ± SEM. Statistics by two-tailed t-test: *P ≤ 0.05; **P ≤ 0.01; vs DIO + FGF21.n = 10Back to article page