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Fig. 2 | BMC Biotechnology

Fig. 2

From: Application of surface plasmon resonance imaging to monitoring G protein-coupled receptor signaling and its modulation in a heterologous expression system

Fig. 2

PKC activation results in an increase in R P/S . (a and b) TPA (100 nM) but not the control vehicle (DMSO) alone increased R P/S in non-transfected HEK293T cells. In this and following figures, the test agent-containging saline was dropped into the measurement chamber after a 5-min basal measurement; the test agent continued to be present in the chamber onward. a Sample images of the reflection of the P-polarized light before and after a 25-min application of the labeled agent. b Mean time-plots of R P/S . Arrow, onset of test agent application. Error bars, ±SEM. ***, p < 0.0001 at 25 min of the test agent application onset (van der Waerden rank sum test)

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BMC Biotechnology

ISSN: 1472-6750

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