Source | Library | Antigen | Pos./all (%) | Comments |
---|---|---|---|---|
Chicken | scFv | Persephine | 18/118 (15 %) | After B-cell capturing as described here, the screening was done using E. coli based system |
GFRα1 | 71/140 (50 %) | |||
scFv-Fc | hDNase | 3/43 (7 %) | ||
hNGF | 3/23 (13 %) | |||
HPV18 E2 | 7/93 (8 %) | Full-length protein was used for immunization but the B-cell capturing and screening were performed using only C-terminal domain (one-third) | ||
Mouse | scFv | Persephine | 19/190 (10 %) | After B-cell capturing as described here, the screening was done using E. coli based system |
scFv-Fc | Artemin | 12/78 (15 %) | ||
hNGF | 7/24 (29 %) | |||
Rabbit | scFv-Fc | hCD48 | 7/46 (15 %) | |
HPV18 E2N-GST | 13/93 (14 %) | |||
HPV18 E2C-GST | 16/188 (9 %) | Summarized results obtained from 2 rabbits | ||
mCD48 | 80/186 (43 %) | |||
Ebola VLP | 25/94 (27 %) | |||
Ebola GP | 104/234 (44 %) | Summarized results obtained from 3 experiments | ||
IgG | Ebola GP | 11/46 (24 %) | ||
mCD48 | 55/94 (59 %) | see section “Screening natural intact IgG molecules” for more details | ||
hBDNF | 43/125 (34 %) |