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Figure 8 | BMC Biotechnology

Figure 8

From: Human IL-12 p40 as a reporter gene for high-throughput screening of engineered mouse embryonic stem cells

Figure 8

Histologic sections of teratomas resulting from in vivo differentiation of mouse ES lines expressing IL-12 p40. Tissues from all three primary cell lineages (endo-, meso-, and ectoderm) were formed in individual teratomas. a-c. Sections from a single teratoma derived from an R1 cell line expressing a high level of IL-12 p40 from pPGK-cIITA-IRES-p40. d-e. Sections from a single teratoma derived from a W9.5 cell line expressing a high level of IL-12 p40 from pPGK-rtTA-IRES-p40. a, d. ciliated epithelium of endodermal origin. b, e. muscle of mesodermal origin. c, f. neuroectoderm.

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BMC Biotechnology

ISSN: 1472-6750

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