Table 1 Influence of different genomic loci on de novo HAC formation
From: Efficient assembly of de novohuman artificial chromosomes from large genomic loci
Genomic Locus | Size (kb) | Location | No. Transfections | Freq. HAC formation1 |
|---|---|---|---|---|
G2 | 100 | 9q33 | 12 | 1/21 (5%) |
G4 | 98 | 8q24.3 | 10 | 8/19 (42%) |
G6 | 90 | 7p13 | 6 | 9/12 (75%) |
G8 | 125 | 15q23 | 5 | 1/8 (12%) |
G10 | 125 | 3p16 | 9 | 3/16 (19%) |
G11 | 100 | 22q11.4 | 11 | 9/33 (27%) |
G14 | 125 | 1q32 | 2 | 3/14 (21%) |
G16 | 97 | 2p23 | 5 | 5/7 (71%) |
G17 | 97 | 4q22 | 8 | 2/19 (10%) |
G19 | 95 | 11p13 | 6 | 1/26 (4%) |
ß-globin | 216 | 11p15.5 | 6 | 7/27 (26%) |
HGH | 159 | 17q24.2 | 8 | 3/16 (19%) |
PKD1 | 208 | 16p13.3 | 10 | 4/19 (21%) |