Figure 3From: Efficient assembly of de novohuman artificial chromosomes from large genomic lociCytogenetic validation of de novo HAC vectors containing the ß-globin genomic locus. A) D17Z1 alpha-satellite (green), BAC vector (red). (B) D17Z1 alpha-satellite (green), ß-globin genomic locus (red). (C) D17Z1 alpha-satellite (green), telomere DNA (red). (D) D17Z1 alpha-satellite (green), CENP-C (red). In all cases, DNA is in blue (DAPI). Arrows point to de novo HACs.Back to article page