Figure 7From: Accuracy and efficiency define Bxb1 integrase as the best of fifteen candidate serine recombinases for the integration of DNA into the human genomeHypothetical mechanism for the origin of the G418rgancyclovirr, attR-, attL-clones generated by the serine integrases during integration reactions. The figure shows a two step model for the origin of the GANCr Neor attL-attR-clones arising during the integration experiments. A illustrates the first step in the model; the deletion of the HyTK gene and B illustrates the second step; the integration of the CCAGneo gene. Further details are discussed in the text.Back to article page