Figure 1From: Enhanced recombinant protein production and differential expression of molecular chaperones in sf-caspase-1-repressed stable cells after baculovirus infectionThe apoptosis pathway in S. frugiperda cells. Apoptotic signals trigger the activation of initiator Sf-caspase-X in S. frugiperda cells. The Op-IAP and Sf-IAP suppress the activation of Sf-caspase-X, which proteolytically activates downstream effector caspases, including Sf-caspase-1, by cleavage at the large-small subunit junction. The activated effector caspases can amplify this processing and different steps are inhibited by P49 and P35.Back to article page