Figure 3
From: Antigen vehiculization particles based on the Z protein of Junin virus
GFP-specific total serum IgG antibody response. A. Groups of Balb/C mice were intramuscularly immunized twice with Z-eGFP VLPs, Z-eGFP VLPs treated with Triton X-100, GFP and PBS (negative control). Blood samples collected at day 35 were 50-fold diluted and used to determine GFP-specific total IgG by ELISA. Optical densities (490 nm) are expressed as the arithmetic means plus standard error. ANOVA one-way analysis (Tukey's Multiple Comparison Test) of variance was used to determine statistical significance between different samples.*; P<0.05. ns; not significant (P>0.05). B. The immunization schedule used in this experiment.