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Figure 1 | BMC Biotechnology

Figure 1

From: Optimization of glutathione production in batch and fed-batch cultures by the wild-type and recombinant strains of the methylotrophic yeast Hansenula polymorphaDL-1

Figure 1

Growth and glutathione accumulation of H. polymorpha DL-1 at fermenter batch cultivations. A - Dry cell weight (DCW); B, C, D - TIG (GSH+GSSGin) and TEG (GSH+GSSGex) concentrations, expressed in nmol/mg protein (B) and in mg/L culture medium (C, D). H. polymorpha DL-1 wild type strain was cultivated with glucose at different modes of pH control and aeration: fermentation with pH control at 5.2 (pH control), fermentation without pH control (w/o pH control), aeration at stirrer speed of 200 rpm (200) and at 600 rpm (600); data for TIG and TEG accumulation at different aeration without pH control and with pH control (C and D, respectively); E - data of dissolved oxygen tension in culture media at different mode of aeration and pH control. Values shown are the means of three independent determinations.

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BMC Biotechnology

ISSN: 1472-6750

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