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  1. Genetic diversity, population structure, agro-morphological traits, and molecular characteristics, are crucial for either preserving genetic resources or developing new cultivars. Due to climate change, water ...

    Authors: Adel A. Elshafei, Eid I. Ibrahim, Kamal F. Abdellatif, Abd El-Azeem K. Salem, Khaled A. Moustafa, Abdullah A. Al-Doss, Hussein M. Migdadi, Amal M. Hussien, Walid Soufan, Taha Abd El Rahman and Samah M. Eldemery
    Citation: BMC Biotechnology 2024 24:41
  2. This study compared the differences of microvesicles (MVs) and microvesicles-delivering Smad7 (Smad7-MVs) on macrophage M1 polarization and fibroblast differentiation in a model of Peyronie’s disease (PD).

    Authors: Wenting Wang, Fengchun Wan, Tianxi Yu, Shuang Wu, Xin Cui, Chongjun Xiang, Monong Li, Qingzuo Liu and Chunhua Lin
    Citation: BMC Biotechnology 2024 24:40
  3. Melia azedarach is known as a medicinal plant that has wide biological activities such as analgesic, antibacterial, and antifungal effects and is used to treat a wide range of diseases such as diarrhea, malaria, ...

    Authors: Vahid Rabbani, Ghasem-Ali Garoosi, Raheem Haddad, Reza Farjaminezhad and Reza Heidari Japelaghi
    Citation: BMC Biotechnology 2024 24:39
  4. Antibiotic-containing carrier systems are one option that offers the advantage of releasing active ingredients over a longer period of time. In vitro sustained drug release from a carrier system consisting of ...

    Authors: Lucas Ritschl, Pia Schilling, Annette Wittmer, Annerose Serr, Hagen Schmal and Michael Seidenstuecker
    Citation: BMC Biotechnology 2024 24:38
  5. As part of a publicly funded initiative to develop genetically engineered Brassicas (cabbage, cauliflower, and canola) expressing Bacillus thuringiensis Crystal (Cry)-encoded insecticidal (Bt) toxin for Indian an...

    Authors: Md Mahmudul Hassan, Francis Tenazas, Adam Williams, Jing-wen Chiu, Charles Robin, Derek A. Russell and John F. Golz
    Citation: BMC Biotechnology 2024 24:37
  6. To establish a strategy for stem cell-related tissue regeneration therapy, human gingival mesenchymal stem cells (hGMSCs) were loaded with three-dimensional (3D) bioengineered Matrigel matrix scaffolds in high...

    Authors: Shukui Xu, Liru Zhao, Yinghui Li, Xiuge Gu, Ziyang Liu, Xing Han, Wenwen Li and Wensheng Ma
    Citation: BMC Biotechnology 2024 24:36
  7. Fusarium head blight (FHB) is a devastating fungal disease affecting different cereals, particularly wheat, and poses a serious threat to global wheat production. Chitinases and β-glucanases are two important ...

    Authors: Negin Mohammadizadeh-Heydari, Masoud Tohidfar, Bahram Maleki Zanjani, Motahhareh Mohsenpour, Rahele Ghanbari Moheb Seraj and Keyvan Esmaeilzadeh-Salestani
    Citation: BMC Biotechnology 2024 24:35
  8. Signal peptide (SP) engineering has proven able to improve production of many proteins yet is a laborious process that still relies on trial and error. mRNA structure around the translational start site is imp...

    Authors: Piers Wilkinson, Brian Jackson, Hazel Fermor and Robert Davies
    Citation: BMC Biotechnology 2024 24:34
  9. β-TCP ceramics are versatile bone substitute materials and show many interactions with cells of the monocyte-macrophage-lineage. The possibility of monocytes entering microporous β-TCP ceramics has however not...

    Authors: Marco Waldmann, Marc Bohner, Long-Quan R. V. Le, Anna Baghnavi, Bianca Riedel and Michael Seidenstuecker
    Citation: BMC Biotechnology 2024 24:32
  10. Pasta assortments fortified with high quality foods are a modern nutritional trends. This study, explored the effects of fortification with linseed flour (LF) and linseed oil (LO) on durum wheat pasta characte...

    Authors: Zahra Amri, Amira Mnari Bhouri, Madiha Dhibi, Mohamed Hammami, Sonia Hammami and Beligh Mechri
    Citation: BMC Biotechnology 2024 24:31
  11. Cyanobacteria represent a rich resource of a wide array of unique bioactive compounds that are proving to be potent sources of anticancer drugs. Selenium nanoparticles (SeNPs) have shown an increasing potentia...

    Authors: Melika Eydelkhani, Shadi Kiabi and Bahareh Nowruzi
    Citation: BMC Biotechnology 2024 24:27
  12. Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease, and it leads to irreversible inflammation in intra-articular joints. Current treatment approaches for RA include non-steroidal anti-infla...

    Authors: Dipesh Kumar Shah, Sumanta Ghosh, Namdev More, Mounika Choppadandi, Mukty Sinha, Sarath Babu Srivalliputtur, Ravichandiran Velayutham and Govinda Kapusetti
    Citation: BMC Biotechnology 2024 24:26
  13. Venous thromboembolism (VTE), is a noteworthy complication in individuals with gastric cancer, but the current diagnosis and treatment methods lack accuracy. In this study, we developed a t-PAIC chemiluminesce...

    Authors: Yu Ji, Yan Qin, Qi Tan, Yanru Qiu, Shuang Han and Xiaowei Qi
    Citation: BMC Biotechnology 2024 24:30
  14. This research investigates the efficacy of a high-performance pilot-scale Internal Circulation Anaerobic Reactor inoculated with Granular Sludge (ICAGSR) for treating cattle slaughterhouse wastewater while con...

    Authors: Mohamed Saad Hellal, Hala M. El-Kamah and Hala Salah Doma
    Citation: BMC Biotechnology 2024 24:29
  15. Scientists know very little about the mechanisms underlying fish skin mucus, despite the fact that it is a component of the immune system. Fish skin mucus is an important component of defence against invasive ...

    Authors: Ahmed N. Alabssawy, Mohammed Abu-Elghait, Ahmad M. Azab, Hassan M. M. Khalaf-Allah, Abdelrahman S. Ashry, Ahmed O. M. Ali, Abu-Bakr A. A. Sabra and Salem S. Salem
    Citation: BMC Biotechnology 2024 24:28
  16. Treatment with tumor-targeted toxins attempts to overcome the disadvantages of conventional cancer therapies by directing a drug’s cytotoxic effect specifically towards cancer cells. However, success with targ...

    Authors: Finn J. Schulze, Mazdak Asadian-Birjand, Michael Pradela, Nicole Niesler, Gregor Nagel and Hendrik Fuchs
    Citation: BMC Biotechnology 2024 24:24
  17. Volumetric loss is one of the challenging issues in muscle tissue structure that causes functio laesa. Tissue engineering of muscle tissue using suitable hydrogels is an alternative to restoring the physiological...

    Authors: Atieh Rezaei Namjoo, Ayla Hassani, Hassan Amini, Fateme Nazaryabrbekoh, Sepideh Saghati, Mohammad Ali Ebrahimi Saadatlou, Ali Baradar Khoshfetrat, Nafiseh Didar Khosrowshahi and Reza Rahbarghazi
    Citation: BMC Biotechnology 2024 24:23
  18. The advancement of AAV vectors into clinical testing has accelerated rapidly over the past two decades. While many of the AAV vectors being utilized in clinical trials are derived from natural serotypes, engin...

    Authors: Sylvia P. Thomas, Marcus M. Spinelli, Amira D. Rghei, Jordyn A. Lopes, Nicole Zielinska, Benjamin M. McLeod, Yanlong Pei, Wei Zhang, Bernard Thebaud, Khalil Karimi and Sarah K. Wootton
    Citation: BMC Biotechnology 2024 24:22
  19. Since the 2000’s, plants have been used as bioreactors for the transient production of molecules of interest such as vaccines. To improve protein yield, “amplicon” vectors based on plant viruses are used. Thes...

    Authors: PKA Bamogo, F Tiendrébéogo, C Brugidou, D Sérémé, FW Djigma, J Simporé and S Lacombe
    Citation: BMC Biotechnology 2024 24:21
  20. Obtaining high-quality chloroplast genome sequences requires chloroplast DNA (cpDNA) samples that meet the sequencing requirements. The quality of extracted cpDNA directly impacts the efficiency and accuracy o...

    Authors: Yifan Yu, Xinxin Wang, Renjun Qu, Zhen OuYang, Juan Guo, Yujun Zhao and Luqi Huang
    Citation: BMC Biotechnology 2024 24:20
  21. Flavonoids are one of the bioactive ingredients of Lonicera macranthoides (L. macranthoides), however, their biosynthesis in the flower is still unclear. In this study, combined transcriptomic and targeted metabo...

    Authors: Ling Ling Lv, Li Yun Li, Long Qian Xiao and Jian Hui Pi
    Citation: BMC Biotechnology 2024 24:19

    The Correction to this article has been published in BMC Biotechnology 2024 24:33

  22. Nanotechnology-based drug delivery systems have received much attention over the past decade. In the present study, we synthesized Methyl Urolithin A-loaded solid lipid nanoparticles decorated with the folic a...

    Authors: Ilham Naeem Abd Ali Al-Fatlawi, Vahid Pouresmaeil, Fatemeh Davoodi-Dehaghani, Aida Pouresmaeil, Ali Akhtari and Masoud Homayouni Tabrizi
    Citation: BMC Biotechnology 2024 24:18
  23. Thermostable DNA polymerases, such as Taq isolated from the thermophilic bacterium Thermus aquaticus, enable one-pot exponential DNA amplification known as polymerase chain reaction (PCR). However, properties oth...

    Authors: Cristina Hernández-Rollán, Anja K. Ehrmann, Arsenios Vlassis, Vijayalakshmi Kandasamy and Morten H. H. Nørholm
    Citation: BMC Biotechnology 2024 24:17
  24. Cancer associated drug resistance is a major cause for cancer aggravation, particularly as conventional therapies have presented limited efficiency, low specificity, resulting in long term deleterious side eff...

    Authors: Mona Elradi, Ahmed I. Ahmed, Ahmed M. Saleh, Khaled M. A. Abdel-Raouf, Lina Berika, Yara Daoud and Asma Amleh
    Citation: BMC Biotechnology 2024 24:14
  25. Smoking was a major risk factor for chronic obstructive pulmonary disease (COPD). This study plan to explore the mechanism of Polyphyllin B in lung injury induced by cigarette smoke (CSE) in COPD.

    Authors: Qing Wang, Zhiyi He, Jinqi Zhu, Mengyun Hu, Liu Yang and Hongzhong Yang
    Citation: BMC Biotechnology 2024 24:13
  26. The objective of this study was to establish a methodology for determining carboxymethyl lysine (CML) and carboxyethyl lysine (CEL) concentrations in human plasma using liquid chromatography-tandem mass spectr...

    Authors: Daguang Wang, Junshan Wang, Xinghong Liu, Kehe Du, Hongjun Liu, Xiaofeng Yang, Tianyi Liu, Qian Liu, Meng Wang and Jian Guo
    Citation: BMC Biotechnology 2024 24:12
  27. One of the current challenges is to secure wheat crop production to meet the increasing global food demand and to face the increase in its purchasing power. Therefore, the current study aimed to exploit a new ...

    Authors: Nashwa H. Abdullah, Nouran A. Elbialy, Mohamed Abdelnaser Amer, Mostafa Kh. Gabr, Amira Salah El-Din Youssef, Mohamed H. Sharaf, M. E. Shehata, Mohamed H. Kalaba and Elham R. S. Soliman
    Citation: BMC Biotechnology 2024 24:11
  28. Polymicrobial communities lead to worsen the wound infections, due to mixed biofilms, increased antibiotic resistance, and altered virulence production. Promising approaches, including enzymes, may overcome th...

    Authors: Sanaz Dehbashi, Hamed Tahmasebi, Mohammad Yousef Alikhani, Mohammad-Ali Shahbazi and Mohammad Reza Arabestani
    Citation: BMC Biotechnology 2024 24:10
  29. The production of Pleurotus ostreatus mycelium as a promising object for use in food and other industries is hampered by a lack of information about the strain-specificity of this fungus mycelium growth and its a...

    Authors: Tetiana Krupodorova, Victor Barshteyn, Victoria Tsygankova, Mustafa Sevindik and Yaroslav Blume
    Citation: BMC Biotechnology 2024 24:9
  30. Silver nanoparticles (Ag-NPs) have a unique mode of action as antibacterial agents in addition to their anticancer and antioxidant properties. In this study, microbial nanotechnology is employed to synthesize ...

    Authors: Mohamed T. Shaaban, Briksam S. Mohamed, Muhammad Zayed and Sabha M. El-Sabbagh
    Citation: BMC Biotechnology 2024 24:8
  31. The Mediterranean fruit fly, Ceratitis capitata, is a significant agricultural pest managed through area-wide integrated pest management (AW-IPM) including a sterile insect technique (SIT) component. Male-only re...

    Authors: Germano Sollazzo, Katerina Nikolouli, Georgia Gouvi, Roswitha A. Aumann, Marc F. Schetelig and Kostas Bourtzis
    Citation: BMC Biotechnology 2024 24:7
  32. L-arginase, is a powerful anticancer that hydrolyzes L-arginine to L-ornithine and urea. This enzyme is widely distributed and expressed in organisms like plants, fungi, however very scarce from bacteria. Our ...

    Authors: Manal S. Selim, Marwa M. Mounier, Sayeda A. Abdelhamid, Ahmed Abdelghani Hamed, Mostafa M. Abo Elsoud and Sahar S. Mohamed
    Citation: BMC Biotechnology 2024 24:6
  33. Modern high-throughput technologies enable the processing of a large number of samples simultaneously, while also providing rapid and accurate procedures. In recent years, automated liquid handling workstation...

    Authors: Giovanni Annona, Assunta Liberti, Carla Pollastro, Antonietta Spagnuolo, Paolo Sordino and Pasquale De Luca
    Citation: BMC Biotechnology 2024 24:4
  34. The growing spread of infectious diseases has become a potential global health threat to human beings. According to WHO reports, in this study, we investigated the impact of co-cultivating the isolated endophy...

    Authors: Ahmed A. Hamed, Mosad A. Ghareeb, Ayda K. Kelany, Mohamed Abdelraof, Hoda A. Kabary, Nariman R. Soliman and Mohamed E. Elawady
    Citation: BMC Biotechnology 2024 24:3
  35. Lytic polysaccharide monooxygenases (LPMOs) catalyzing the oxidative cleavage of different types of polysaccharides have potential to be used in various industries. However, AA13 family LPMOs which specificall...

    Authors: Meijuan Zhang, Xiaoping Fu, Rongrong Gu, Bohua Zhao, Xingya Zhao, Hui Song, Hongchen Zheng, Jianyong Xu and Wenqin Bai
    Citation: BMC Biotechnology 2024 24:2
  36. The chimeric antigen receptor-expressing T (CAR-T) cells for cancer immunotherapy have obtained considerable clinical importance. CAR T cells need an optimized intracellular signaling domain to get appropriate...

    Authors: Fatemeh Hajari Taheri, Mahmoud Hassani, Zahra Sharifzadeh, Mahdi Behdani, Shahryar Abdoli, Mahtab Sayadi, Kowsar Bagherzadeh, Arash Arashkia and Mohsen Abolhassani
    Citation: BMC Biotechnology 2024 24:1
  37. In tissue engineering (TE) and regenerative medicine, the accessibility of engineered scaffolds that modulate inflammatory states is extremely necessary. The aim of the current work was to assess the efficacy ...

    Authors: Akram Firouzi Amandi, Seyed Abbas Shahrtash, Shaylan Kalavi, Afshin Moliani, Hanieh Mousazadeh, Mehdi Rezai Seghin Sara and Mehdi Dadashpour
    Citation: BMC Biotechnology 2023 23:55
  38. Probiotics are viable microorganisms that when administered in adequate amounts confer health benefits to the host. In fish, probiotic administration has improved growth, and immunological parameters. For this...

    Authors: Marcelo Fernando Valle-Vargas, Ruth Yolanda Ruiz-Pardo, Luisa Villamil-Díaz and María Ximena Quintanilla-Carvajal
    Citation: BMC Biotechnology 2023 23:54
  39. Vitamin B12 (VB12) has a wide range of applications and high economic value. In this study, a new strain with high VB12 production potential, Ensifer adhaerens S305, was identified in sewage. Because E. adhaerens

    Authors: Yongheng Liu, Wei Huang, Qi Wang, Cilang Ma, Yongyong Chang and Jianyu Su
    Citation: BMC Biotechnology 2023 23:53
  40. In this study, we designed a novel genetic circuit sensitive to Cd2+, Zn2+ and Pb2+ by mimicking the CadA/CadR operon system mediated heavy metal homeostasis mechanism of Pseudomonas aeruginosa. The regular DNA m...

    Authors: H. M. L. P. B. Herath, W. R. M. de Silva, R. S. Dassanayake, Y. I. N. S. Gunawardene, J. R. P. Jayasingha, M. K. Gayashan, L. O. B. Afonso and K. M. N. de Silva
    Citation: BMC Biotechnology 2023 23:52
  41. Goat rumen microbial communities are perceived as one of the most potential biochemical reservoirs of multi-functional enzymes, which are applicable to enhance wide array of bioprocesses such as the hydrolysis...

    Authors: Santosh Thapa, Suping Zhou, Joshua O’Hair, Kamal Al Nasr, Alexander Ropelewski and Hui Li
    Citation: BMC Biotechnology 2023 23:51
  42. Filamentous fungi are efficient degraders of plant biomass and the primary producers of commercial cellulolytic enzymes. While the transcriptional regulation mechanisms of cellulases have been continuously exp...

    Authors: Fanglei Xue, Zhen Zhao, Shuying Gu, Meixin Chen, Jing Xu, Xuegang Luo, Jingen Li and Chaoguang Tian
    Citation: BMC Biotechnology 2023 23:50
  43. A lot of kitchen waste oil is produced every day worldwide, leading to serious environmental pollution. As one of the environmental protection methods, microorganisms are widely used treating of various wastes...

    Authors: Xinran Duan, Wei Zhai, Xintian Li, Sicheng Wu, Ye Wang, Lixia Wang, Wangdui Basang, Yanbin Zhu and Yunhang Gao
    Citation: BMC Biotechnology 2023 23:48
  44. γ-polyglutamic acid (γ-PGA) is a biomarker that can be directly obtained by microbial fermentation. Poly(amino acid) superabsorbent polymers (SAPs) were prepared with purified γ-PGA as raw material and ethylen...

    Authors: Zhao Jianbo, Wei Jun, Wang Xuanlin and Cao Hui
    Citation: BMC Biotechnology 2023 23:47

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