Skip to content

Advertisement

You're viewing the new version of our site. Please leave us feedback.

Learn more

BMC Biotechnology

Proteomics and drug discovery

Section edited by Igor Stagljar

This section will consider studies that focus on proteomics and protein-protein interactions, and their application in drug discovery, testing and targeting.This section will consider studies that focus on proteomics and protein-protein interactions, and their application in drug discovery, testing and targeting.

  1. Content type: Methodology article

    Targeted delivery of gene therapy vectors to the mouse respiratory tract is often performed via intranasal or intratracheal administration; however, there can be a great deal of variability between these metho...

    Authors: Lisa A. Santry, Joelle C. Ingrao, Darrick L. Yu, Jondavid G. de Jong, Laura P. van Lieshout, Geoffrey A. Wood and Sarah K. Wootton

    Citation: BMC Biotechnology 2017 17:43

    Published on:

  2. Content type: Methodology article

    G protein-coupled receptors (GPCRs) are ubiquitous surface proteins mediating various biological responses and thus, important targets for therapeutic drugs. GPCRs individually produce their own signaling as w...

    Authors: Yuki Nonobe, Tomoki Yokoyama, Yuji Kamikubo, Sho Yoshida, Nozomi Hisajima, Hiroaki Shinohara, Yuki Shiraishi, Takashi Sakurai and Toshihide Tabata

    Citation: BMC Biotechnology 2016 16:36

    Published on:

  3. Content type: Research article

    Fluorescence-enhancing microarray on plasmonic gold film is an attractive alternative to traditional enzyme-linked immunosorbent assay (ELISA) for cytokine detection because of the increased sensitivity. The a...

    Authors: Manfè Valentina, Fleckner Jan, Nørby Lisby Peder, Zhang Bo, Dai Hongjie and Keller Pernille

    Citation: BMC Biotechnology 2015 15:73

    Published on:

  4. Content type: Research article

    γ-Glutamyl transpeptidase 1 (GGT1) is an N-glycosylated membrane protein that catabolizes extracellular glutathione and other γ-glutamyl-containing substrates. In a variety of disease states, including tumor form...

    Authors: Matthew B West, Katie Partyka, Christa L Feasley, Kevin A Maupin, Indiwari Goppallawa, Christopher M West, Brian B Haab and Marie H Hanigan

    Citation: BMC Biotechnology 2014 14:101

    Published on:

  5. Content type: Research article

    So-called cyathane type diterpenoids are produced as secondary metabolites by basidiomycetes. Based on their antibacterial, fungicidal, and cytotoxic properties, cyathane type terpenoids represent interesting ...

    Authors: Tian Shen, Lena M Hof, Heike Hausmann, Marc Stadler and Holger Zorn

    Citation: BMC Biotechnology 2014 14:98

    Published on:

  6. Content type: Research article

    O. stamineus is a medicinal herb with remarkable pharmacological properties. However, poor solubility of the active principles limits its medicinal value. This study sought to prepare nano liposomes of OS ethanol...

    Authors: Abdalrahim FA Aisha, Amin Malik Shah Abdul Majid and Zhari Ismail

    Citation: BMC Biotechnology 2014 14:23

    Published on:

  7. Content type: Research article

    Protein Kinases are key regulators of cell function and play essential roles in the occurrence and development of many human diseases. Many kinase inhibitors have been used for molecular targeted treatment of ...

    Authors: Xiao-Yun Lu, Ming-Chuan Li, Xin-Liang Zhu, Fan Fan, Lei-Lei Wang and Jian-Gang Ma

    Citation: BMC Biotechnology 2014 14:4

    Published on:

  8. Content type: Research article

    Monoclonal antibody therapeutics are rapidly gaining in popularity for the treatment of a myriad of diseases, ranging from cancer to autoimmune diseases and neurological diseases. Multiple forms of antibody th...

    Authors: Sean H Gao, Kexin Huang, Hua Tu and Adam S Adler

    Citation: BMC Biotechnology 2013 13:55

    Published on:

  9. Content type: Research article

    Mitochondrial outer membrane permeabilization (MOMP) is a crucial step leading to apoptotic destruction of cancer cells. Bcl-2 family proteins delicately regulate mitochondrial outer membrane integrity through...

    Authors: Jianting Long, Liu Liu, Zaneta Nikolovska-Coleska, Sanjeev Shangary, Han Yi, Shenming Wang and Shaomeng Wang

    Citation: BMC Biotechnology 2013 13:45

    Published on:

  10. Content type: Correspondence

    The high-throughput genomics communities have been successfully using standardized spreadsheet-based formats to capture and share data within labs and among public repositories. The nanomedicine community has ...

    Authors: Dennis G Thomas, Sharon Gaheen, Stacey L Harper, Martin Fritts, Fred Klaessig, Elizabeth Hahn-Dantona, David Paik, Sue Pan, Grace A Stafford, Elaine T Freund, Juli D Klemm and Nathan A Baker

    Citation: BMC Biotechnology 2013 13:2

    Published on: