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Cellular and tissue engineering

Section edited by Joaquim Cabral

This section will consider articles that relate to stem cell research and regenerative medicine as well as cell culture methods and bioproduction in animal cells.


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  1. There is an increasing need to understand cell-cell interactions for cell and tissue engineering purposes, such as optimizing cell sheet constructs, as well as for examining adhesion defect diseases. For cell-...

    Authors: Qi Wei, Daniel Reidler, Min Ye Shen and Hayden Huang

    Citation: BMC Biotechnology 2013 13:17

    Content type: Research article

    Published on:

  2. Guanylate binding protein-1 (GBP-1) is a large GTPase which is actively secreted by endothelial cells. It is a marker and intracellular inhibitor of endothelial cell proliferation, migration, and invasion. We ...

    Authors: Oliver Bleiziffer, Matthias Hammon, Andreas Arkudas, Christian D Taeger, Justus P Beier, Kerstin Amann, Elisabeth Naschberger, Michael Stürzl, Raymund E Horch and Ulrich Kneser

    Citation: BMC Biotechnology 2012 12:94

    Content type: Research article

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  3. Despite positive reports on the efficacy of stem cell therapy for the treatment of cardiovascular disease, the nature of stem cell homing to ischemic tissues remains elusive.

    Authors: Bert R Everaert, Irene Bergwerf, Nathalie De Vocht, Peter Ponsaerts, Annemie Van Der Linden, Jean-Pierre Timmermans and Christiaan J Vrints

    Citation: BMC Biotechnology 2012 12:93

    Content type: Research article

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  4. Induced pluripotent stem (iPS) cells can differentiate into any cell type, which makes them an attractive resource in fields such as regenerative medicine, drug screening, or in vitro toxicology. The most importa...

    Authors: Hiroyuki Koike, Koji Kubota, Keisuke Sekine, Takanori Takebe, Rie Ouchi, Yun-Wen Zheng, Yasuharu Ueno, Naoki Tanigawa and Hideki Taniguchi

    Citation: BMC Biotechnology 2012 12:81

    Content type: Methodology article

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  5. In modern biotechnology, there is a need for pausing cell lines by cold storage to adapt large-scale cell cultures to the variable demand for their products. We compared various cell culture media/solutions fo...

    Authors: Gesine Pless-Petig, Martin Metzenmacher, Tobias R Türk and Ursula Rauen

    Citation: BMC Biotechnology 2012 12:73

    Content type: Research article

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  6. Integrin-mediated interaction of neuronal cells with extracellular matrix (ECM) is important for the control of cell adhesion, morphology, motility, and differentiation in both in vitro and in vivo systems. Arg-G...

    Authors: Won Bae Jeon, Bo Hyung Park, Seong Kyoon Choi, Kyeong-Min Lee and Jin-Kyu Park

    Citation: BMC Biotechnology 2012 12:61

    Content type: Research article

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  7. Achieving efficient introduction of plasmid DNA into primary cultures of mammalian cells is a common problem in biomedical research. Human primary cranial suture cells are derived from the connective mesenchym...

    Authors: Prem P Dwivedi, Peter J Anderson and Barry C Powell

    Citation: BMC Biotechnology 2012 12:45

    Content type: Methodology article

    Published on:

  8. Diabetes mellitus is a complicated disease with a pathophysiology that includes hyperinsulinemia, hyperglycemia and other metabolic impairments leading to many clinical complications. It is necessary to develo...

    Authors: Mina Rasouli, Zalinah Ahmad, Abdul Rahman Omar and Zeenathul N Allaudin

    Citation: BMC Biotechnology 2011 11:99

    Content type: Research article

    Published on: