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Applied immunology

This section will consider studies on protein or cell engineering as they apply to the functions of the immune system and have applications in diagnostics, therapy and biomedical research.


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  1. Interleukin-1 receptor antagonist, a cytokine that is highly therapeutic to rheumatoid arthritis and several other inflammatory diseases, exhibits rapid blood clearance and poor retention time on the target in...

    Authors: Mengyuan Liu, Yi Huang, Lei Hu, Guoping Liu, Xueping Hu, Dongxu Liu and Xiaosong Yang

    Citation: BMC Biotechnology 2012 12:68

    Content type: Research article

    Published on:

  2. Cell panning of phage-displayed antibody library is a powerful tool for the development of therapeutic and imaging agents since disease-related cell surface proteins in native complex conformation can be direc...

    Authors: Hyerim Yoon, Jin Myung Song, Chun Jeih Ryu, Yeon-Gu Kim, Eun Kyo Lee, Sunghyun Kang and Sang Jick Kim

    Citation: BMC Biotechnology 2012 12:62

    Content type: Methodology article

    Published on:

  3. Costimulation of T cells via costimulatory molecules such as B7 is important for eliciting cell-mediated antitumor immunity. Presenting costimulation molecules by immobilizing recombinant B7 on the surface of ...

    Authors: Ming-Chuan Li, Qian-Qian Liu, Xiao-Yun Lu, Ya-Li Zhang and Lei-Lei Wang

    Citation: BMC Biotechnology 2012 12:43

    Content type: Research article

    Published on:

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