Table 3 Cell cycle associated protein DE at day 6 and/or 10 between high and low peak VCD CDCLs

G3HVL1

CDK1

Cell division control protein 2-like

Up in high VCD

1.74

Up in high peak VCD

G3GXH4

CDK6

Cell division protein kinase 6

Up in high VCD

G3GV30

EML4

Echinoderm microtubule-associated protein-like 4 (Fragment)

Up in high VCD

G3H7V9

MCM2

DNA helicase

Up in high VCD

2.63

Up in high peak VCD

G3IAI5

MCM5

DNA helicase

Up in high VCD

2.59

Up in high peak VCD

G3H5Q3

MSH2

DNA mismatch repair protein

Up in high VCD

G3H5Q5

MSH6

DNA mismatch repair protein

Up in high VCD

G3GUM5

NCAPD2

Condensin complex subunit 1

Up in high VCD

4.88

Up in high peak VCD

G3HR05

NCAPG

Condensin complex subunit 3

Up in high VCD

5.07

Up in high peak VCD

G3IBF6

PDS5A

Sister chromatid cohesion protein PDS5-like A

Up in high VCD

G3HYF3

POLA1

DNA polymerase

Up in high VCD

G3I732

POLD1

DNA polymerase

Up in high VCD

G3HRM7

PRIM1

DNA primase

Up in high VCD

G3GUU6

PRKCD

Non-specific serine/threonine protein kinase

Up in high VCD

G3IJB6

RCC2

Protein RCC2

Up in high VCD

2.08

Up in high peak VCD

G3IAU0

SMC4

Uncharacterized protein (Fragment)

Up in high VCD

2.73

Up in high peak VCD

G3HJS1

SPTBN1

Spectrin beta chain, brain 1

Up in high VCD

G3I2J5

SUN2

Protein unc-84-like B

Up in high VCD

G3HMC7

TBRG4

Protein TBRG4

Up in high VCD

G3ILQ1

TRIP13

Thyroid receptor-interacting protein 13

Up in high VCD

G3HK64

TUBGCP3

Gamma-tubulin complex component

Up in high VCD

G3HHD8

VRK1

Serine/threonine-protein kinase VRK1

Up in high VCD

G3GXR7

MAPRE3

Microtubule-associated protein RP/EB family member 3

Up in low peak VCD

G3HYW2

MCTS1

Malignant T cell amplified sequence 1

Up in low peak VCD

G3H2N6

PDCD6IP

Programmed cell death 6-interacting protein

Up in low peak VCD

G3H3D3

BCAT1

Branched-chain-amino-acid aminotransferase

87.94

Up in high peak VCD

G3I5V6

BUB3

Mitotic checkpoint protein BUB3

2.16

Up in high peak VCD

G3GUY5

CCAR2

Protein KIAA1967-like

1.77

Up in high peak VCD

Q2MH30

DHFR

Dihydrofolate reductase

3.44

Up in high peak VCD

G3H9Z5

EPS8

Epidermal growth factor receptor kinase substrate 8

1.85

Up in high peak VCD

G3H354

HSP90AA1

Heat shock protein HSP 90-alpha

1.52

Up in high peak VCD

Up in high peak VCD

G3I1H0

MCM3

DNA helicase

2.75

Up in high peak VCD

G3I2I1

MCM4

DNA helicase

2.42

Up in high peak VCD

G3IAI5

MCM5

DNA helicase

2.59

Up in high peak VCD

G3GZQ9

MCM6

DNA helicase

2.57

Up in high peak VCD

G3IFZ0

MKI67

Antigen KI-67

24.45

Up in high peak VCD

G3HR05

NCAPG

Condensin complex subunit 3

5.07

Up in high peak VCD

G3HC95

NSUN2

tRNA (Cytosine-5-)-methyltransferase NSUN2

1.56

Up in high peak VCD

G3H412

PCNA

Proliferating cell nuclear antigen

2.72

Up in high peak VCD

G3IFL1

PPAT

Amidophosphoribosyltransferase

2.07

Up in high peak VCD

G3IP86

RPA1

Replication protein A 70 kDa DNA-binding subunit

1.52

Up in high peak VCD

G3IDS7

SLC16A1

Monocarboxylate transporter 1

1.64

Up in high peak VCD

G3GTY6

SMC2

Structural maintenance of chromosomes protein 2

5.64

Up in high peak VCD

G3IAU0

SMC4

Uncharacterized protein (Fragment)

2.73

Up in high peak VCD

G3I5N5

TOP2A

DNA topoisomerase 2

10.44

Up in high peak VCD

G3ILQ1

TRIP13

Thyroid receptor-interacting protein 13

2.59

Up in high peak VCD

G3HLY0

TUBG1

Tubulin gamma chain

2.15

Up in high peak VCD

G3IFY1

TYMS

TYMS

2.59

Up in high peak VCD

G3HT32

CUL2

CUL2

1.71

Up in high peak VCD

G3HM24

NEK7

Serine/threonine-protein kinase Nek7

1.73

Up in high peak VCD

G3GV75

RALA

RALA

1.50

Up in high peak VCD