Fig. 4From: Optimization of expression, purification and secretion of functional recombinant human growth hormone in Escherichia coli using modified staphylococcal protein a signal peptideSignal peptide prediction. (a) Spa signal (native), (b) Signal (jei36c). Sec/SPI: standard” secretory signal peptides transported by the Sec translocon and cleaved by Signal Peptidase I; Tat signal peptides (Tat/SPI), which direct their proteins through a twin-arginine translocation; Sec/SPII: lipoprotein signal peptides transported by the Sec translocon and cleaved by Signal Peptidase IIBack to article page