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Fig. 2 | BMC Biotechnology

Fig. 2

From: Optimization of expression, purification and secretion of functional recombinant human growth hormone in Escherichia coli using modified staphylococcal protein a signal peptide

Fig. 2

General structure of the natural sec-dependent signal sequences and alignment of the native and modified signal peptide for secretion of hGH. Panel A is a schematic of the S. aureus signal peptide showing the Ala-X-Ala box consensus that is a peptidase cleavage site. This panel also shows the presence of different domains in the sec-dependent signal sequences. Panel (B) Shows alignment and comparison of the amino acid sequence of natural secretive signal (No. 1) and the amino acid sequence of the modified secretive signal (No. 2)

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BMC Biotechnology

ISSN: 1472-6750

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