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Table 4 Differentially expressed genes encoding KstDs and KshA/B

From: Different genome-wide transcriptome responses of Nocardioides simplex VKM Ac-2033D to phytosterol and cortisone 21-acetate

Locus_tag

Ortholog in Mtb

Localization

Product

q-value Phyt/Ca

Phyt/C

q-value AcC/Cb

AcC/C

KR76_14170

kshA

Cluster А

3-ketosteroid-9α-hydroxylase

2.24E-55

10.9

1

1.3

KR76_27070

kshA

Cluster D

3-ketosteroid-9α-hydroxylase

3.15E-59

14.4

1

1

KR76_14160

kshB

Cluster А

3-ketosteroid-9α-hydroxylase

0.7

1.9

1

1.2

KR76_27080

kshB

Cluster D

3-ketosteroid-9α-hydroxylase

1

3.7

1

1

KR76_02655

kstD1

Out of clusters

3-ketosteroid-Δ1-dehydrogenase

1.01E-07

5.2

1

1.4

KR76_27115

kstD1

Cluster D

3-ketosteroid-Δ1-dehydrogenase

1.4E-131

16.7

1

1.2

KR76_27125

kstD2

Cluster D

3-ketosteroid-Δ1-dehydrogenase

1.44E-14

6.4

0

1207.7

KR76_01140

kstD3

Out of clusters

3-ketosteroid-Δ1-dehydrogenase

1

0.3

1

0.3

KR76_14500

kstD3

Cluster А

3-ketosteroid-Δ1-dehydrogenase

1.12E-12

6.7

1

1

  1. aPhyt/C – expression changes on Phytosterol with respect to control
  2. bAcC/C – expression changes on AcC with respect to control