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Table 1 A summary of select KEGG enrichment genes discovered in ammonia-stressed cultures that can be linked to genome instability in humans via text mining

From: Characterization of metabolic responses, genetic variations, and microsatellite instability in ammonia-stressed CHO cells grown in fed-batch cultures

Gene Name (Human) Entrez Gene ID (Human) Entrez Gene ID (Chinese hamster)
Tumor necrosis factor superfamily member 11 (TNFSF11) 8600 100,768,715
Peroxisome proliferator activated receptor gamma (PPARG) 5468 100,689,245
Interleukin 1 alpha (IL1A) 3552 100,769,260
Wnt family member 1 (WNT1) 7471 100,766,046
Protein phosphatase 1 catalytic subunit alpha (PPP1CA) 5499 100,760,810
Transforming growth factor beta receptor 1 (TGFBR1) 7046 100,772,727
E2F transcription factor 4 (E2F4) 1874 100,765,561
Frizzled class receptor 2 (FZD2) 2535 100,763,109
LDL receptor related protein 6 (LRP6) 4040 100,772,150
Tuberous sclerosis 2 (TSC2) 7249 100,755,849
lin-9 DREAM MuvB core complex component (LIN9) 286,826 100,774,401
BRCA1, DNA repair associated (BRCA1) 672 100,770,724
Mitogen-activated protein kinase kinase 1 (MAP 2 K1) 5604 100,689,403
Protein kinase AMP-activated non-catalytic subunit gamma 3 (PRKAG3) 53,632 100,770,459
Activating transcription factor 2 (ATF2) 1386 100,754,663
RB1 inducible coiled-coil 1 (RB1CC1) 9821 100,763,340
Progesterone receptor (PGR) 5241 100,757,656
fms related tyrosine kinase 4 (FLT4) 2324 100,766,609
Klotho (KL) 9365 100,758,189
Notch 1 (NOTCH1) 4851 100,761,880
Beta-transducin repeat containing E3 ubiquitin protein ligase (BTRC) 8945 100,750,426
Nuclear factor kappa B subunit 1 (NFKB1) 4790 100,770,607
Tumor protein p53 (TP53) 7157 100,682,525
Cyclin E1 (CCNE1) 898 100,753,358
Notch 2 (NOTCH2) 4853 100,771,788