Fig. 2

3D structure of the SAG1 dimer. This image is based on PDB 1ynt [17]. The six disulfide bonds in each monomer are depicted as yellow “double balls”. The two magenta circles at the top mark the N-terminal proline of the solved structure (Pro₃₄ in Fig. 1); the single smaller one the C-terminal glycine (Gly₂₈₆ in Fig. 1) in one of the monomers. Ball-and-stick structures in black and cyan are lysines, whereby the grey arrow heads mark those that are particularly surface-exposed (also visible by the cyan-colored surface cloud). The discontinuous epitope of each monomer is apparent by its blue surface cloud (blue stars) and the individual deep blue-colored residues (see Fig. 1 for their position)