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Table 1 IC50 of CD64 targeted recombinant immunotoxins

From: Evaluation of Hydra HALT-1 as a toxin moiety for recombinant immunotoxin

Recombinant immunotoxinCell lineIC50 (nM)References
H22(scFv)-ETAHL600.17[26]
H22(scFv)-ETAU9370.14[25]
H22(scFv)2-ETAU9370.014[25]
granzymeB-H22(scFv)U9371.7–17[40]
H22(scFv)-MAPHL600.04[27]
HALT-1-scFvTHP-1189This study
HALT-1-scFvHeLa339.96This study
scFv-HALT-1THP-1196.64This study
scFv-HALT-1HeLa371.54This study