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Fig. 6 | BMC Biotechnology

Fig. 6

From: Recombinant PAL/PilE/FlaA DNA vaccine provides protective immunity against Legionella pneumophila in BALB/c mice

Fig. 6

The production levels of cytokines from splenocytes extracted from mice at 16 h after a lethal challenge with Legionella pneumophila. The supernatants of splenocytes were collected after culture for 12, 24, 48, and 72 h. The levels of TNF-α (a), IFNγ (b), IL-12 (c), IL-4 (d), and IL-10 (e) were determined by ELISA kits. All data were expressed as mean ± SD (n = 3). ***P < 0.001 versus the L.p-pcDNA3.1 group

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