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Fig. 2 | BMC Biotechnology

Fig. 2

From: Tuning the performance of CAR T cell immunotherapies

Fig. 2

Aspects of CAR T cell culture and modifications that may be suited to different applications. A typical experiment that involves CAR T cells should consider various aspects of target cell populations, vector and expression system alternatives, structural aspects of the chimeric receptor protein and whether additional cargo should be delivered along with the CAR to the recipient cells. Importantly, gene editing of the CAR T cells may be a critical component of the design process. This is an original diagram

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