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Fig. 3 | BMC Biotechnology

Fig. 3

From: Sustained transgene expression from sleeping beauty DNA transposons containing a core fragment of the HNRPA2B1-CBX3 ubiquitous chromatin opening element (UCOE)

Fig. 3

Several transcription factors can be recruited to the endogenous CBX3-HNRPA2B1 locus and may regulate UCOE function. Schematic illustration of the endogenous CBX3-HNRPA2B1 locus with layered H3K4Me3 and H3K27Ac ChIP-seq tracks from the ENCODE project and overview of conserved transcription factor binding sites from ConTra v3 overlapping with ENCODE transcription factor ChIP-seq peaks. Each bar represents an overlapping region from a specific transcription factor (CEBPB: red, CTCF: blue, EP300: pink, MYC: green, SP1: yellow, YY1: brown). The location of the 1.5 kb HNRPA2B1-CBX3 UCOE region (1.5UCOE) is indicated as is the derived UCOE-CORE. Scale bar: 100 bp

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