TY - JOUR AU - Veras, Henrique C. T. AU - Campos, Christiane G. AU - Nascimento, Igor F. AU - Abdelnur, Patrícia V. AU - Almeida, João R. M. AU - Parachin, Nádia S. PY - 2019 DA - 2019/08/05 TI - Metabolic flux analysis for metabolome data validation of naturally xylose-fermenting yeasts JO - BMC Biotechnology SP - 58 VL - 19 IS - 1 AB - Efficient xylose fermentation still demands knowledge regarding xylose catabolism. In this study, metabolic flux analysis (MFA) and metabolomics were used to improve our understanding of xylose metabolism. Thus, a stoichiometric model was constructed to simulate the intracellular carbon flux and used to validate the metabolome data collected within xylose catabolic pathways of non-Saccharomyces xylose utilizing yeasts. SN - 1472-6750 UR - https://doi.org/10.1186/s12896-019-0548-0 DO - 10.1186/s12896-019-0548-0 ID - Veras2019 ER -