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Fig. 2 | BMC Biotechnology

Fig. 2

From: VARSCOT: variant-aware detection and scoring enables sensitive and personalized off-target detection for CRISPR-Cas9

Fig. 2

Comparison of the VARSCOT pipeline (a) Receiver Operating Characteristic (ROC) curves of VARSCOT and other off-target activity models tested on the Test Dataset. b Number of potential off-targets detected by the VARSCOT, Elevation and CRISPOR pipelines compared to the off-targets detected experimentally in the Test Dataset. c Effect of a threshold on the True Positive Rate (TPR) and False Positive Rate (FRP) of detection of VARSCOT

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