Skip to main content

Table 2 Phytosterol inducible expression changes of known sterol catabolism genes

From: Genome-wide response on phytosterol in 9-hydroxyandrostenedione-producing strain of Mycobacterium sp. VKM Ac-1817D

Gene name Locus Expression increasing Function of ortholog References
ltp3 G155_04795 96.89 Aldol lyase [17]
ltp4 G155_04800 96.38 Aldol lyase [17]
echA19 G155_04835 68.59 Enoyl-CoA hydratase [2]
fadD19 G155_04840 97.53 Long-chain fatty-acid-CoA ligase [47]
fadD17 G155_04880 81.64 Long-chain fatty-acid-CoA ligase [18]
chsE5(fadE27) G155_04885 74.14 Acyl-CoA dehydrogenase [48]
chsE4(fadE26) G155_04890 89.21 Acyl-CoA dehydrogenase [48]
ltp2 G155_26150 69.08 Putative thiolase [49]
chsH1 G155_26155 66.32 Steroid enoyl-CoA hydratase [50]
chsH2 G155_26160 62.40 Steroid enoyl-CoA hydratase [50]
chsE2(fadE29) G155_26165 76.45 Acyl-CoA dehydrogenase [20]
chsE1(fadE28) G155_26170 58.19 Acyl-CoA dehydrogenase [20]
cyp125 G155_26175 107.58 C26-steroid monooxygenase [14]
fadA5 G155_26180 136.07 Acetyl-CoA acetyltransferase [19]
chsE3(fadE34) G155_26510 50.22 Acyl-CoA dehydrogenase [51]
kstD G155_04625 61.43 3-oxosteroid 1-dehydrogenase [52]
4kstD G155_08770 10.09 3-oxosteroid 1-dehydrogenase [53]
hsaE G155_04630 11.57 2-keto-4-pentenoate hydratase [25]
hsaG G155_04635 9.95 Acetaldehyde dehydrogenase [25]
hsaF G155_04640 7.13 4-hydroxy-2-oxovalerate aldolase [25]
kshA_1 G155_04755 55.51 3-ketosteroid-9-alpha-hydroxylase oxygenase subunit [21]
kshA_2 G155_24375 24.58 3-ketosteroid-9-alpha-hydroxylase oxygenase subunit [21]
hsaB G155_26470 26.88 Monooxygenase component B [26]
hsaC G155_26475 26.18 2,3-dihydroxybiphenyl 1,2-dioxygenase  
hsaD G155_26480 32.34 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase [27]
hsaA G155_26485 34.01 Monooxygenase component A [26]
kshB G155_26490 39.90 3-ketosteroid-9-alpha-hydroxylase reductase subunit [21]
hsd G155_22700 83.36 3-hydroxysteroid dehydrogenase [54]
Hsd4A G155_04900 11.12 17β- hydroxysteroid dehydrogenase [55]
echA20 G155_26220 9.82 Putative enoyl-CoA hydratase [38]
ipdA G155_26225 8.61 Putative CoA-transferase subunit alpha [38]
ipdB G155_26230 8.35 Putative CoA-transferase subunit beta [38]
fadA6 G155_26270 16.55 3-ketoacyl-CoA thiolase, acetyl-CoA acetyltransferase [38]
fadE30 G155_26335 10.49 Acyl-CoA dehydrogenase [38]
fadD3 G155_26340 9.84 Fatty-acid-CoA ligase [38]
fadE31 G155_26345 8.60 Acyl-CoA dehydrogenase [38]
fadE32 G155_26350 7.51 Acyl-CoA dehydrogenase [38]
fadE33 G155_26355 8.45 Acyl-CoA dehydrogenase [38]
kstR G155_26515 13.17 Transcriptional regulator, TetR family [28]
kstR2 G155_26275 15.81 Transcriptional regulator, TetR family [36]
yrbEA G155_04905 3.58 Conserved hypothetical integral membrane protein [56]
yrbEB G155_04910 3.71 Conserved hypothetical integral membrane protein [56]
mceA G155_04915 3.21 MCE-family protein [56]
mceB G155_04920 3.63 MCE-family protein [56]
mceC G155_04925 3.67 MCE-family protein [56]
mceD G155_04930 3.40 MCE-family protein [56]
mceE G155_04935 3.87 MCE-family protein [56]
mceF G155_04940 3.17 MCE-family protein [56]
mas4B G155_04950 3.07 MCE-associated protein [56]