Fig. 4

Measurement of luc2-modified xenograft cell growth in a co-culture system. Xenograft cells (1 × 104 cells/well) were co-cultured with two different cell types as described in Methods in (a) 2D culture model; and (b) 3D culture model. Luminescence was measured at Day 4. Left panel: XenoB110-gfp-luc2; Right panel: Xeno284-gfp-luc2. Results are represented by average of triplicate from 3 mice ± SD. * p < 0.05