Skip to main content
Fig. 7 | BMC Biotechnology

Fig. 7

From: Novel anti-CD38 humanized mAb SG003 possessed enhanced cytotoxicity in lymphoma than Daratumumab via antibody-dependent cell-mediated cytotoxicity

Fig. 7

SG003 inhibits outgrowth of CD38-expressing Raji xenografts in SCID mice model. a Light emission of mice from the back side. SCID mice were inoculated with luciferase-expressing Raji cells, and 100 μg/mouse SG003 was injected to inhibit the tumor growth. Mice infused with Daratumumab or human IgG (100 μg/mouse) were set as positive or negative controls. b Survival Rate of Raji xenograft mice (n = 6). The experiments were done twice SG003 had satisfactory anti-tumor activity in vivo. 3 mice in SG003 group were alive at the endpoint, which was obviously higher than control group (G1, all dead), and even the Daratumumab-treated group (G2, 1 mouse alive)

Back to article page

BMC Biotechnology

ISSN: 1472-6750

Contact us